Year: 2022 | Month: April | Volume 12 | Issue 2

Immunostimulatory Effect of Indian Herbs Tinospora cordifolia and Asparagus racemosus on Ranikhet Disease Vaccination in Chickens

V. Govind S. Venkateswarlu I. Hemanth K. Harshavardhan P. Mounika P. Anand Kumar
DOI:10.30954/2277-940X.02.2022.21

Abstract:

Ranikhet disease (RD) is important infectious disease of chicken. Although vaccination available, sometimes immunosupression induced by factors like stress lead to vaccination failures. Immunostimulation by using of herbs in Ayurveda for enhancing the general host immune status is well documented. Present study is aimed to investigate the immunostimulatory effect of important Indian herbs Guduchi (Tinospora cordifolia) and Shatavari (Asparagus racemosus) on RD vaccination in chickens. Stem dry powder of Guduchi and root dry powder of Shatavari were mixed in regular poultry feed to different groups of birds. All the groups of birds were vaccinated with primary, 1st booster and 2nd booster doses of RD vaccine and the sera samples were tested for antibody levels by hemagglutination inhibition (HI) test. Significant higher (p < 0.001) HI antibody titers were found in Shatavari supplemented group and in both the herbs supplemented groups of chickens after 1st and 2nd booster doses of RD vaccination in comparison to RD vaccinated control group. However, Guduchi didn’t show any significant immunostimulating properties on RD vaccination after 1st booster and 2nd booster doses of vaccination.



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